Uso de antihipertensivos como factor protector para fractura no traumática de cadera

Nuñez  Marinovich-Milenka

doi:10.37711/rpcs.2023.5.3.423

Authors

Nuñez Marinovich-Milenka Universidad Privada Antenor Orrego, La Libertad-Trujillo, Perú https://orcid.org/0009-0004-7654-2014

DOI:

https://doi.org/10.37711/rpcs.2023.5.3.423

Keywords:

antihypertensives, risk reduction, nontraumatic, fracture

Abstract

Objective. To determine whether the use of antihypertensives is associated with reduced risk of nontraumatic hip fracture in patients at Hospital Belén de Trujillo, 2017-2022. Methods. A retrospective, analytical, cross-sectional study was conducted. According to the selection criteria, 160 adult patients were included and divided into 2 groups: with or without nontraumatic hip fracture; then, the prevalence ratio and the chi-square statistical test were applied. Results. Mean age and frequency of osteoporosis were significantly higher in the group of patients with hip fracture (p < 0.05). The consumption of thiazide antihypertensives was a protective factor for non-traumatic hip fracture, with a prevalence ratio of 0.29, which was significant (p < 0.05). The use of beta-blockers was a protective factor for non-traumatic hip fracture, with a prevalence ratio of 0.30, which was significant (p < 0.05). The use of ARBs was a protective factor for non-traumatic hip fracture, with a prevalence ratio of 0.26, which was significant (p < 0.05). The consumption of ACEI was not a protective factor for non-traumatic hip fracture, with a prevalence ratio of 1.11, which was not significant (p > 0.05). Conclusions. The use of antihypertensives is associated with decreased risk of nontraumatic hip fracture in patients at Hospital Belén de Trujillo, 2017-2022 (level of evidence III-B)

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