Anemia y síntomas de depresión en pacientes con cáncer de mama temprano en el Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú

Sandro Casavilca-Zambrano; Nilton Custodio; Ruddy Liendo-Picoaga; Karina Cancino-Maldonado; Rosa Montesinos; Stéphane  Bertani; Laura Fejerman; Jorge Honles; Luis Argumanis; Fiorella Baca; Maëlenn Guerchet; Tatiana Vidaurre

doi:10.37711/rpcs.2022.4.3.377

Authors

Sandro Casavilca-Zambrano Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú https://orcid.org/0000-0001-8406-739X
Nilton Custodio Instituto Peruano de Neurociencias, Lima, Perú. https://orcid.org/0000-0002-8025-3272
Ruddy Liendo-Picoaga Universidad Científica del Sur, Lima, Perú https://orcid.org/0000-0003-3570-8802
Karina Cancino-Maldonado Banco de Tejidos Tumorales, Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú. https://orcid.org/0000-0002-6343-8785
Rosa Montesinos Instituto Peruano de Neurociencias, Lima, Perú. https://orcid.org/0000-0002-9342-8756
Stéphane Bertani Université de Toulouse, IRD, UPS, Toulouse, France. https://orcid.org/0000-0002-0398-9745
Laura Fejerman University of California Davis, Davis, CA, United States. https://orcid.org/0000-0003-3179-1151
Jorge Honles Université de Toulouse, UMR 152 PHARMADEV, IRD, UPS, Toulouse, France. https://orcid.org/0000-0003-3015-5321
Luis Argumanis Departamento de Hematología, Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú. https://orcid.org/0000-0002-8048-8848
Fiorella Baca Université de Limoges, INSERM, IRD, limoges, France. https://orcid.org/0000-0001-5112-0828
Maëlenn Guerchet Université de Limoges, INSERM, IRD, limoges, France https://orcid.org/0000-0002-0470-5556
Tatiana Vidaurre Departamento de Oncología Médica, Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú. https://orcid.org/0000-0003-1995-4560

DOI:

https://doi.org/10.37711/rpcs.2022.4.3.377

Keywords:

anemia, breast cancer, depression, diagnosis, morbidity, mortality

Abstract

Objective. The aim of this study was to determine the relationship between anemia and depressive symptoms in patients with early stage breast cancer at the National Institute of Neoplastic Diseases (INEN), Lima, Peru. Methods. An analytical cross-sectional observational study of 60 Peruvian women diagnosed with early stage I and II breast cancer was conducted between June 2019 and March 2020. All participants were assessed by Beck Depression Inventory-II (BDIII) score, had not received prior chemotherapy, and met the inclusion criteria. Each participant provided a blood sample that was used to estimate hemoglobin and red and white blood cell counts. Results. Of the 60 patients who met the inclusion criteria, twenty (33.3%) had depressive symptoms at the time of diagnosis. Mean hemoglobin levels in patients with depressive symptoms (M = 10.9, SD = 2.1) were lower compared to those in patients without depression (M = 13.6, SD =1, p =
0.004). A limitation of our study was the small sample size and the fact that thyroid hormones and vitamin B12 were not tested. Conclusions. Our study found a significant difference in hemoglobin levels among breast cancer patients with symptoms of depression. Interventions to address the presence of anemia and depression in women with breast cancer are needed to improve health outcomes in these patients.

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