La influencia de las hormonas sexuales en la salud cardiovascular: perspectivas actuales y direcciones futuras

Autores/as

  • Kirolos Eskandar Diakonie Klinik Mosbach

DOI:

https://doi.org/10.37711/rpcs.2024.6.2.449

Palabras clave:

Sex hormones, Cardiovascular health, Estrogen, testosterone, hormone replacement therapy, personalized medicine, healthcare equity

Resumen

La intrincada relación entre las hormonas sexuales y la salud cardiovascular ha atraído cada vez más atención, revelando implicaciones significativas tanto para la prevención de enfermedades como para las estrategias terapéuticas. Esta revisión de la literatura tiene como objetivo dilucidar las funciones multifacéticas de los estrógenos, la progesterona y la testosterona en la fisiología y patología cardiovascular. El estrógeno es ampliamente reconocido por sus efectos protectores sobre la función vascular, el metabolismo de los lípidos y la prevención de la aterosclerosis, mientras que la testosterona presenta un cuadro más complejo con impactos tanto beneficiosos como perjudiciales sobre el riesgo cardiovascular. La progesterona, que a menudo se pasa por alto, también desempeña un papel fundamental en la modulación de estos efectos. Además, esta revisión explora cómo las hormonas sexuales influyen en la función endotelial, las respuestas inflamatorias y contribuyen a las diferencias de género en la prevalencia de enfermedades cardiovasculares. Se examina críticamente el impacto de la menopausia y la terapia de reemplazo hormonal (TRH) en la salud cardiovascular, destacando los debates en curso y las pautas actuales. Además, se discuten las implicaciones cardiovasculares de la terapia hormonal de afirmación del género en personas transgénero. Al sintetizar las perspectivas actuales e identificar futuras direcciones de investigación, esta revisión subraya el potencial de los enfoques de medicina personalizada que consideran el estado hormonal para optimizar los resultados de salud cardiovascular.

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Citas

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Publicado

2024-04-02

Cómo citar

1.
Eskandar K. La influencia de las hormonas sexuales en la salud cardiovascular: perspectivas actuales y direcciones futuras. revista de salud udh [Internet]. 2 de abril de 2024 [citado 21 de julio de 2024];6(2). Disponible en: http://revistas.udh.edu.pe/index.php/RPCS/article/view/574